Hello everyone!
I know many here are having problems with the issue mouse not being locked in game screen.
I have 2 monitors and I had this issue last night when I launched Sea Of Thieves.
Either you install Dual Monitor Tools as LadyHaradaNiwa posted on X (Twitter) See the post here
Or you do following method
Now I fixed my issue with making changes on Windows registry itself but I'd like someone who doesn't have Dual Monitor Tools installed and having the same issue to try following
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Now those steps fixed issue on my side, I hope it does the same for you. Now I cannot promise 100% fix for you guys as I already installed Dual Monitor Tools on my system.
Let me know if this helped you.